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Pharmacokinetics after oral administration c max of citalopram in plasma is achieved within 2-4 hours.

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Although in controlled studies Celexa has not been shown to impair psychomotor performanceany psychoactive drug may impair judgmentthinkingor motor skillsso patients should be cautioned about operating hazardous machineryincluding automobilesuntil they are reasonably certain that Celexa therapy does not affect their ability to engage in such activities.

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Neonates exposed to Celexa and other SSRIs or serotonin and norepinephrine reuptake inhibitorsSNRIslate in the third trimesterhave developed complications requiring prolonged hospitalizationrespiratory supportand tube feedingSuch complications can arise immediately upon deliveryReported clinical findings have included respiratory distresscyanosisapneaseizurestemperature instabilityfeeding difficultyvomitinghypoglycemiahypotoniahypertoniahyperreflexiatremorjitterinessirritabilityand constant cryingThese features are consistent with either a direct toxic effect of SSRIs and SNRIs orpossiblya drug How much mobicel discontinuation syndromeIt should be noted thatin some casesthe clinical picture is consistent with serotonin syndromesee WARNINGSSerotonin Syndrome

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escitalopram may cause problems in newborns following delivery if it is taken during the last months of pregnancy.